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No matter what they do through diet and exercise, it will not make those thoughts of food go away, Levy says, which makes it nearly impossible to lose weight and keep it off. How GLP-1 Drugs Help Quiet Food Noise While, according to a story on Everyday Healths network site Lose It!, the exact reason these drugs quiet food noise isnt yet clear, its likely related to their ability to boost production of GLP-1, a hormone made in the gut and released in response to food that helps people realize when theyve had enough to eat, Levy says